Modular organization of the catalytic center of RNA polymerase
نویسندگان
چکیده
منابع مشابه
Modular organization of the catalytic center of RNA polymerase.
The Fe2+ ion that specifically replaces Mg2+ in the active center of RNA polymerase generates reactive hydroxyl radicals that cause highly localized cleavage of polypeptide chains. Mapping of the cleavage sites revealed the overall architecture of the active center. Nine distinct sites, five in the beta subunit and four in the beta' subunit of Escherichia coli RNA polymerase, all at or near hig...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1997
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.94.13.6641